PrEP, short for pre-exposure prophylaxis, can be administered as a daily pill or a bimonthly shot. Users can take the tablets on demand, that is, before having planned sex. Approved in 2012 by the FDA, the drug eliminates the risk of contracting the virus after exposure. The Centers for Disease Control and Prevention has confirmed that the increased use of PrEP, along with increased testing and treatment, has played an important role in the recent decline in new HIV infections.